产品货号：
Z12133
中文名称：
BEX3抗体
英文名称：
Anti-BEX3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BEX3 Antibody |
| 指标别名 | Bex,BEX3,NADE,HGR74,DXS6984E,Protein BEX3,Brain-expressed X-linked protein 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | BEX3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NADE antibody was raised against a peptide corresponding to 14 amino acids near the middle of human NADE.The immunogen is located within the last 50 amino acids of NADE. |
| 计算分子量 | 13kDa |
| 成分 | NADE Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NADE Antibody is Ion exchange chromatography purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF).The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR.Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac).Co-expression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization.It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed.Finally,although initially discovered as an mRNA expressed in ovarian granulosa cells,NADE has been suggested to play a role in the neuronal death seen in epileptic brain damage. |
| Uniprot ID | Q00994 |
| 基因名全称 | Nerve growth factor receptor (TNFRSF16) associated protein 1 |
| 蛋白名全称 | Nerve growth factor receptor (TNFRSF16) associated protein 1 |
| 推荐稀释比 | NADE antibody can be used for detection of NADE by Western blot at 1μg/mL.Despite its predicted molecular weight,NADE migrates at~23kDa in SDS-PAGE.Antibody can also be used for immunohistochemistry starting at 2μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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